Mechanisms of Cellular Organization
Fall 2008
Room 2-501 BSB
MWF 2:30 - 3:30
| Rob Piper (Co-Director) |
Molecular Physiology & Biophysics | 6-452 BSB | 335-7842 | robert-piper@uiowa.edu
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| Mark Stamnes (Co-Director) |
Molecular Physiology & Biophysics | 5-550 BSB | 335-7858 | mark-stamnes@uiowa.edu |
| Charles Yeaman | Anatomy & Cell Biology | 1-632 BSB | 335-8782 | charles-yeaman@uiowa.edu |
| Lee-Ann Allen | Internal Medicine | D154 MTF | 335-4258 | lee-ann-allen@uiowa.edu |
| David Sheff | Pharmacology | 2-570 BSB | 335-7705 | david-sheff@uiowa.edu |
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25
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Monday
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Organization of course.
Introduction to Membranes
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Piper
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SPECIFIC AIMS ASSIGNED
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27
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Wednesday
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How proteins cross membranes;
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Piper
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29
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Friday
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How proteins cross membranes -
continued
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Piper
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Homework #1 asigned
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SEPTEMBER
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| 1 | Monday
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LABOR DAY |
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3
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Wednesday
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Discussion of Homework
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Piper
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no points |
| 5 | Friday | Functions of the endoplasmic reticulum and Golgi | Piper | Homework #2 Assigned | |
| 8
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Monday
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Cellular response to damaged proteins
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Piper
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10 |
Wednesday
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Vesicle formation at the ER
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Piper
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12
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Friday
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Discussion of Homework
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Piper
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25
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15
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Monday |
Vesicle formation at the Golgi and TGN
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Piper
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| 17 | Wednesday
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Membrane fusion - SNARE and Rab
function
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Sheff
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Homework #3 assigned
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19
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Friday |
Exocytosis |
Sheff
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22
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Monday |
Discussion of Homework |
Sheff
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Homework #3 Due
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25
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24
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Wednesday
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Friday
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The endosomal system
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Sheff
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Homework #4 Assigned
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| 29 | Monday | Discussion/Review Discuss Homework 4 |
Sheff | EXAM A POSTED
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OCTOBER
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1
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Wednesday
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Lysosomes
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Sheff
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3
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Friday
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Actin and actin binding
proteins
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Sheff
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6 |
Monday |
Cell motility and Rho GTPases
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STAMNES
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8
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Wednesday |
Actin-based motility continued
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STAMNES
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10
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Friday
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Discussion of Homework |
STAMNES
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| 13
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15
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Wednesday
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MAPs and intermediate filaments
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STAMNES
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17
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Friday
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Discussion of Homework
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STAMNES
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20
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Monday
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Molecular motors
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STAMNES
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22
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Wednesday
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EXAM (B)-In class
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STAMNES
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EXAM B
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50
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24
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Friday
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Cilia and Flagella I
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YEAMAN
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27
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Monday
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Cilia and Flagella II
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YEAMAN
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Homework #7 Assigned
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29
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Wednesday
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Nuclear-cytoplasmic transport
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YEAMAN
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31
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NOVEMBER
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Monday
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Mitosis I: Changes in nuclear
& cytoplasmic organization (Prophase through metaphase)
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YEAMAN
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5 |
Wednesday
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Mitosis II: Changes in nuclear
& cytoplasmic organization (anaphase through cytokinesis)
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YEAMAN
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7
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Friday
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Mitochondrial function
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YEAMAN
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Homework #8 Assigned
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10
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12
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Wednesday
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Discussion of Homework
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YEAMAN
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Homework #8 Due
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No points
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| 14 | Friday | Peroxisome biogensis | Allen
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17
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Monday
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Phagocytosis - Macrophages
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Allen
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19
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| 21 | Friday
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Host-pathogen interactions I
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Homework #9 Assigned | ||
24
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Monday
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THANKSGIVING |
Allen
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26
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Wednesday
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THANKSGIVING |
Allen
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