Molecular & Cellular Biology Program molcell-biology@uiowa.edu University of Iowa 357 Medical Research Center Iowa City, IA 52242-1182 Phone: 800-551-6787 or 319-335-7748 Fax: 319-335-7656
Invesigates the molecular biology of hormone action and hormone receptors in reproductive tissues
Dr. Leslie's laboratory investigates the molecular biology of hormone action and hormone receptors in reproductive tissues. Her greatest research contribution has focused on the response to steroid stimulation and the phenotypic and genomic mechanisms in endometrial cancer. New areas of focus include sub-cellular localization of progesterone receptors, proteomics as a tool for cancer screening, and progesterone receptor cross-talk with the growth factors and other signaling molecules. Dr. Leslie’s laboratory has also made observations pertaining to the molecular pathways affected in preeclampsia, and these findings were the subject of plenary talks at the Society for Maternal-Fetal Medicine meetings in 2008 and 2009. Dr. Leslie continues to be active in the clinical care of women with pregnancy complications and serves as an examiner for the American Board of Obstetrics and Gynecology.
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